Michael A. Henry, DDS, PhD
D.D.S., University of Washington School of Dentistry
Ph.D., University of Washington School of Medicine
Certificate, Facial Pain, University of Florida College of Dentistry
Neuroanatomy, Trigeminal, Electron Microscopy, Confocal Microscopy, Orofacial, Pain, Immunocytochemistry, Regenerative Endodontics
My primary research interests are related to the neuroanatomical basis for pain transmission and modulation within the trigeminal system. These interests are tied to my clinical background with training in Orofacial Pain and as an Orofacial Pain clinician. A major focus of these studies has involved changes in sodium channel expression in painful human dental pulp as a model for inflammatory pain and in the rat trigeminal system following nerve lesions as a model for neuropathic pain. More recent studies are evaluating contributions from glia, immune and vascular systems to these inflammatory and neuropathic pain conditions, and stem-cell based therapies to regenerate the human pulpodentin complex. These studies are mostly accomplished with the use of the confocal microscope and the application of quantitative analysis techniques that objectively evaluate differences in immunofluorescence intensity within structures located in painful tissues as compared to normal tissues.